In the Netherlands, almost all inhabitants are listed with a general practitioner (GP) / family physician (FP), who deals with all health problems requiring professional medical care and is the gatekeeper to specialist care. The Dutch health care is explained here.

FaMe-Net is the continuation of two PBRNs, that merged in 2013: the Continuous Morbidity Registration (CMR) Nijmegen, which has been registering epidemiology since 1967, and the ‘Transition Project’ from Amsterdam, which has been registering since 1985. Both are built around episode registration, in which all information belonging to one health problem comes together in an episode of care.

The founding father of the world’s first PBRN (the Continuous Morbidity Registration) was Frans Huygen. He was a professor of general practice / family medicine in Nijmegen, the Netherlands, who studied morbidity patterns in families using data from the CMR. He published the first edition of the medical textbook ‘Family Medicine’ in 1978, describing family medicine using data from the CMR.

The founding father of the Transition Project was Henk Lamberts. He was a professor of general practice in Amsterdam (University of Amsterdam) and one of the co-authors of ICPC-1 and ICPC-2. He also developed the concept of the Reason For Encounter.

Inge Okkes described the validity and the value of this concept in her PhD thesis.
With the Dutch textbooks “In het huis van de huisarts” (1991) and “Van Klacht naar diagnose” (1998) they published scientific standard works describing general practice (family medicine) using epidemiological data collected during the Transition Project.

FaMe-Net uses since 2025 HealthConnected as the electronic patient record in which the care provided in the general practices is recorded. The previous electronic health record was named TransHis. Currently, Annemarie Uijen is the chair of FaMe-Net.